Simpotentin, a new potentiator of amphotericin B activity against Candida albicans, produced by Simplicillium minatense FKI-4981

Uchida R., Kondo A., Yagi A., Nonaka K., Masuma R., Kobayashi K., Tomoda H. 

J. Antibiot. 72, 134-140 (2018)

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MS network-based screening for new antibiotics discovery

Koyama N., Tomoda H.

J. Antibiot. 72, 54-56 (2018)

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Helvamide, a new inhibitor of sterol O-acyltransferase produced by the fungus Aspergillus nidulans BF-0142

Fukuda T., Furukawa T., Kobayashi K., Nagai K., Uchida R., Tomoda H. 

J. Antibiot. 72, 8-14 (2018)

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真菌由来マルチ銅酸化酵素の新しい機能

供田　洋 

化学 73, 43-46 (2018)

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Celludinones, new inhibitors of sterol O-acyltransferase, produced by Talaromyces cellulolyticus BF-0307

Ohshiro T., Seki R., Fukuda T., Uchida R., Tomoda H.

J. Antibiot. 71, 1000-1007 (2018)

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A mixture of atropisomers enhances neutral lipid degradation in mammalian cells with autophagy induction

Kobayashi K., Ohte S., Ohshiro T., Ugaki N., Tomoda H.

Sci. Rep. 8, 12099 (2018)

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Sydowianumols A, B, and C, Three New Compounds from Discomycete Poculum pseudosydowianum

Kawashima D., Hosoya T., Tomoda H., Kita M., Shigemori H.

Chem. Pharm. Bull. 66, 826-829 (2018)

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Anti-Rhizopus activity of tanzawaic acids produced by the hot spring-derived fungus Penicillium sp. BF-0005

Tominaga T., Uchida R., Koyama N., Tomoda H. 

J. Antibiot. 71, 626-632 (2018)

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Callyspongiamides A and B, sterol O-acyltransferase inhibitors, from the Indonesian marine sponge Callyspongia sp. 

Kapojos MM., Abdjul DB., Yamazaki H., Ohshiro T., Rotinsulu H., Wewengkang DS., Sumilat DA., Tomoda H., Namikoshi M., Uchida R. 

Bioorg. Med. Chem. Lett. 28, 1911-1914 (2018)

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脂肪性肝疾患予防治療薬の開発状況と展望

大城　太一，供田　洋 

バイオインダストリー 35, 36-44 (2018)

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Saturated fatty acids undergo intracellular crystallization and activate the NLRP3 inflammasome in macrophages

Karasawa T., Kawashima A., Usui-Kawanishi F., Watanabe S., Kimura H., Kamata R., Shirasuna K., Koyama Y., Sato-Tomita A., Matsuzaka T., Tomoda H., Park SY. Shibayama N., Shimano H., Kasahara T., Takahashi M.

Arterioscler. Thromb. Vasc. Biol. 38, 744-756 (2018)

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Discovery of a fungal multi copper oxidase that catalyzes the regioselective coupling of a tricyclic naphthopyranone to produce atropisomers

Kawaguchi M., Ohshiro T., Toyoda M., Ohte S., Inokoshi J., Fujii I., Tomoda H

Angew. Chem. Int. Ed. Engl. 57, 5115-5119 (2018)

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Design and synthesis of A-ring simplified pyripyropene A analogues as potent and selective synthetic SOAT2 inhibitors

Ohtawa M., Arima S., Ichida N., Terayama T., Ohio H., Yamazaki T., Ohshiro T., Sato N., Omura S., Tomoda H., Nagamitsu T. 

ChemMedChem 13, 411-421 (2018)

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Caldorin, a new polyketide from the marine cyanobacterium Caldora Penicillata

Shiota I., Iwasaki A., Sumimoto S., Tomoda H., Suenaga K. 

Tetrahedron Lett. 59, 1261-1263 (2018)