Discovery of new hazimycin congeners from Kitasatospora sp. P07101

Koyama N., Sato H., Tomoda H. 

Acta. Pharm. Sin. B 5, 564-568 (2015)

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Three New Chlorinated Cyclopentenols, Palmaenols A and B and Palmaetriol, from the Discomycete Lachnum palmae

Tanabe Y., Matsumoto T., Hosoya T., Tomoda H., Shiro M., Shigemori H.

Nat. Prod. Commun. 10, 1981-1984 (2015)

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Identification and characterization of natural microbial products that alter the free d-aspartate content of mammalian cells

Katane M., Kaneko Y., Watanabe M., Doi Y., Tanaka T., Kasuga Y., Yoshida N., Kumakubo S., Nakayama K., Matsuda S., Furuchi T., Saitoh Y., Sekine M., Koyama N., Tomoda H., Homma H. 

Bioorg. Med. Chem. Lett. 26, 556-560 (2015)

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New pyripyropene A derivatives, Highly SOAT2-selective Inhibitors, Improve hypercholesterolemia and atherosclerosis in atherogenic mouse models

Ohshiro T., Ohtawa M., Nagamitsu T., Matsuda D., Yagyu H., Davis M., Rudel L.L., Ishibashi S., Tomoda H. 

J. Pharmacol. Exp. Ther. 355, 299-309 (2015)

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Nicotinic acetylcholine receptors mediate donepezil-induced oligodendrocyte differentiation

Imamura O., Arai M., Dateki M., Ogata T., Uchida R., Tomoda H., Takishima K.

J. Neurochem. 135, 1086-1098 (2015)

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PRD125, a potent and selective inhibitor of sterol O-acyltransferase 2 markedly reduces hepatic cholesteryl ester accumulation and improves liver function in lysosomal acid lipase-deficient mice.

Lopez A.M., Chuang J.C., Posey K.S., Ohshiro T., Tomoda H., Rudel L.L., Turley S.D.

J. Pharmacol. Exp. Ther. 355, 159-167 (2015)

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Graphiumins I and J, new thiodiketopiperazines from the marine-derived fungus Graphium sp. OPMF00224

Fukuda T., Nagai K., Kurihara Y., Kanamoto A., Tomoda H.

Nat. Prod. Sci. 21, 255-260 (2015)

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Clonoamide, a new inhibitor of sterol O-acyltransferase, produced by Clonostachys sp. BF-0131.

Kobayashi K., Tsukasaki N., Uchida R., Yamaguchi Y., Tomoda H. 

J. Antibiot. 68, 615-619 (2015)

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Diketopiperazines, inhibitors of sterol O-acyltransferase, produced by a marine-derived Nocardiopsis sp. KM2-16. 

Kobayashi K., Fukuda T., Terahara T., Harunari E., Imada C., Tomoda H. 

J. Antibiot. 68, 638-641 (2015)

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Graphiumins, new thiodiketopiperazines from the marine-derived fungus Graphium sp. OPMF00224

Fukuda T., Shinkai M., Sasaki E., Nagai K., Kurihara Y., Kanamoto A., Tomoda H.

J. Antibiot. 68, 620-627 (2015)

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