Isomethoxyneihumicin, a new cytotoxic agent produced by marine Nocardiopsis alba KM6-1

Fukuda T., Takahashi M., Nagai K., Harunari E., Imada C., Tomoda H.

J. Antibiot. 70, 590-594 (2016)

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Discovery of SOAT2 inhibitors from synthetic small molecules

Kobayashi K., Ohshiro T., Tomoda H., Yin F., Cui H.L., Chouthaiwale P.V., Tanaka F.

Bioorg. Med. Chem. Lett. 26, 5899-5901 (2016)

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Beauvericin counteracted multi-drug resistant Candida albicans by blocking ABC transporters

Tong Y., Liu M., Zhang Y., Liu X., Huang R., Song F., Dai H., Ren B., Sun N., Pei G., Bian J., Jia X.M., Huang G., Zhou X., Li S., Zhang B., Fukuda T., Tomoda H., Ōmura S., Cannon R.D., Calderone R., Zhang L. 

Synth. Syst. Biotechnol. 25, 158-168 (2016)

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Synthesis and Structural Revision of Cyslabdan

Ohtawa M., Hishinuma Y., Takagi E., Yamada T., Ito F., Arima S., Uchida R., Kim Y.P., Ōmura S., 
Tomoda H., Nagamitsu T. 

Chem. Pharm. Bull. 64, 1370-1377 (2016)

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7-Chlorofolipastatin, an inhibitor of sterol O-acyltransferase, produced by marine-derived Aspergillus ungui NKH-007

Uchida R.,  Nakajyo K.,  Kobayashi K.,  Ohshiro T.,  Terahara T.,  Imada C.,  Tomoda H.

J. Antibiot. 69, 647-651 (2016)

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Simplifungin and valsafungins, antifungal antibiotics of fungal origin

Ishijima H., Uchida R., Ohtawa M., Kondo A., Nagai K., Shima K., Nonaka K., Masuma R., Iwamoto S., Onodera H., Nagamitsu T., Tomoda H.

J. Org. Chem. 81, 7373-7383 (2016)

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Pyranonigrin L, A new antioxidant, Produced by the hot spring-derived fungus Penicillium adametzii BF-0003

Uchida R., Miyazaki H., Yamaguchi Y., Ishijima H., Tomoda H.

Nat. Prod. Commun. 11, 1111-1114 (2016)

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Structure-Activity Analysis of Gram-positive Bacterium-producing Lasso Peptides with Anti-mycobacterial Activity

Inokoshi J., Koyama N., Miyake M., Shimizu Y., Tomoda H. 

Sci. Rep. 26, 30375 (2016)

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Helvafuranone produced by the fungus Aspergillus nidulans BF0142 isolated from hot spring-derived soil

Furukawa T., Fukuda T., Nagai K., Uchida R., Tomoda H. 

Nat. Prod. Commun. 11, 1001-1003 (2016)

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Design, Synthesis, and Biological Evaluation of Beauveriolide Analogues Bearing Photoreactive Amino Acids

Masuda Y., Aoyama K., Yoshida M., Kobayashi K., Ohshiro T., Tomoda H., Doi T. 

Chem. Pharm. Bull. 64, 754-765 (2016)

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Inhibition of bacterial undecaprenyl pyrophosphate synthase by small fungal molecules

Inokoshi J., Nakamura Y., Komada S., Komatsu K., Umeyama H., Tomoda H.

J. Antibiot. 69, 798-805 (2016)

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Biosynthesis of mercapturic acid derivative of labdane-type diterpene, cyslabdan: Cyslabdan is generated by mycothiol-mediated xenobiotic detoxification.

Ikeda H., Shin-ya K., Nagamitsu T., Tomoda H.

J. Indust. Microbiol. Biotech. 43, 325-342 (2016)

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Therapeutic effects of three trichothecenes in the silkworm infection assay with Candida albicans

Uchida R., Namiguchi S., Ishijima H., Tomoda H.

Drug Discov. Ther. 10, 44-48 (2016)

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黄色ブドウ球菌の生産する黄色色素生成をターゲットとした阻害剤の探索

福田　隆志、小山　信裕、下山　健太、長光　亨、供田　洋

化学工業. 67, 687-1695 (2016)

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New Approaches to Drug Discovery for Combating MRSA

Tomoda H.

Chem. Pharm. Bull. 64, 104-111 (2016)

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Discovery of new hazimycin congeners from Kitasatospora sp. P07101

Koyama N., Sato H., Tomoda H.

Acta. Pharm. Sin. B 5, 564-568 (2016)